Syed Rizwan Abbas and Qurat ul Ain DOWNLOAD PDF

Abstract Typhoid fever is caused by a most harmful organism Salmonella Typhi. It is the major widespread disease which affects both young and adult in their productive ages. More than 60 lakh per year cases of typhoid are noted in the Indian subcontinent. The main reservoir of salmonella typhi is Human beings. Through faecal and oral routes this disease transferred to a human. In India, some cases of Multidrug-resistant typhoid are noted while in Pakistan extremely drug-resistant cases of typhoid are reported from many years. In India recent report shows that ceftriaxone is the first line of drug which is 100% vulnerable to Salmonella typhi. Better hygiene, adequate water management, proper use of antibiotics and appropriate use of vaccination of typhoid will decrease the burden of disease. The primary source of antibiotics is natural products which were obtained from microorganisms. Medicinal plants exhibit significant bioactivities and with the increasing demand of these herbal medicines, the screening of medicinal herbs for the formation of chemical compounds has become a very efficient way of forming antibiotics. From centuries alternative herbal medicine has been used to cure various infections. Natural plants contain phytoconstituents which have similar chemical properties as of synthetic antibiotics. The increasing number of antibiotic-resistant strains has encouraged researchers to discover new methods of treatment for these diseases. Patients who suffer resistance to antibiotics need longer time for hospitalization to recover from that disease. Some studies focus on traditional therapy using plants, not only for typhoid fever but also other infectious and metabolic diseases. Plants contain chemical compounds which may become the active source of antibiotics and they contain an active ingredient which may help to overcome the problem of resistance against many microorganisms. Moreover, these medicinal plants role is promising which act as a potential agent for curing typhoid fever of natural plant sources. In future plants may be the source of effective treatments against typhoid and many more diseases.