Syed Mubashar Sabir and Syed Rizwan Abbas DOWNLOAD PDF
Abstract
The present study was aimed to evaluate the inhibitory effect of Zizypus jujuba fruit against lipid peroxidation in mice brain and liver homogenates. The antioxidant activity was performed by lipid peroxidation assay while, total phenolic and flavonoid contents were determined spectrophotometrically. The hot water extract prepared from fruit showed significant (P<0.05) inhibition against lipid peroxidation in mice brain and liver homogenates. The high antioxidant activity of Zizypus jujuba is due the presence of high content of phenolic and flavonoids. The results suggest that different accessions of Zizypus jujuba are potential source of antioxidants and have therapeutic effect of disease induced by oxidative stress.
Key words: Zizypus jujuba; Antioxidant activity; Lipid peroxidation; Phenolics; Flavonoids.